Mazen Noureddin Selected Research

Bile Acids and Salts (Bile Acids)

1/2023	Placebo Adverse Events in Non-alcoholic Steatohepatitis Clinical Trials: A Pooled Analysis of 2,944 Participants.
12/2022	A Class Effect Network Meta-analysis of Lipid Modulation in Non-alcoholic Steatohepatitis for Dyslipidemia.
1/2022	Predictive and Prognostic Roles of Gut Microbial Variation in Liver Transplant.
1/2022	Meta-analysis: analysis of mechanistic pathways in the treatment of non-alcoholic steatohepatitis. Evidence from a Bayesian network meta-analysis.
1/2022	Nonalcoholic Steatohepatitis Drug Development Pipeline: An Update.
1/2021	Combination Therapies Including Cilofexor and Firsocostat for Bridging Fibrosis and Cirrhosis Attributable to NASH.
1/2020	Cilofexor, a Nonsteroidal FXR Agonist, in Patients With Noncirrhotic NASH: A Phase 2 Randomized Controlled Trial.
12/2018	Microbiome and bile acid profiles in duodenal aspirates from patients with liver cirrhosis: The Microbiome, Microbial Markers and Liver Disease Study.

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Mazen Noureddin Research Topics

Disease

70	Non-alcoholic Fatty Liver Disease 03/2024 - 09/2012
48	Fibrosis (Cirrhosis) 03/2024 - 10/2010
15	Liver Cirrhosis (Hepatic Cirrhosis) 01/2024 - 12/2018
13	Fatty Liver 01/2024 - 01/2017
12	Liver Diseases (Liver Disease) 03/2024 - 09/2016
11	Inflammation (Inflammations) 12/2022 - 11/2013
9	Hepatocellular Carcinoma (Hepatoma) 12/2023 - 04/2012
9	Neoplasms (Cancer) 11/2023 - 01/2017
8	Obesity 01/2023 - 05/2015
7	Infections 11/2023 - 01/2012
6	Pruritus (Itching) 01/2023 - 01/2020
6	Insulin Resistance 01/2022 - 06/2015
5	Overweight 07/2023 - 10/2019
5	Weight Loss (Weight Reduction) 01/2023 - 09/2017
5	Alcoholic Fatty Liver 12/2022 - 02/2020
5	Hepatitis C 03/2018 - 10/2011
4	Disease Progression 07/2023 - 09/2017
4	Body Weight (Weight, Body) 01/2023 - 12/2013
4	Type 2 Diabetes Mellitus (MODY) 01/2023 - 06/2015
4	Cardiovascular Diseases (Cardiovascular Disease) 01/2023 - 07/2020
4	Liver Neoplasms (Liver Cancer) 11/2022 - 03/2007
4	Chronic Hepatitis C 01/2014 - 09/2010
3	Hemorrhage 08/2023 - 03/2017
3	Biliary Liver Cirrhosis (Primary Biliary Cirrhosis) 01/2023 - 10/2015
3	Varicose Veins (Varicose Vein) 01/2023 - 01/2020
3	Esophageal and Gastric Varices (Esophageal Varices) 01/2023 - 01/2020
3	Endotoxemia 10/2020 - 10/2008
3	End Stage Liver Disease 01/2020 - 03/2017
2	Neoplasm Metastasis (Metastasis) 11/2023 - 11/2023
2	Ascites 08/2023 - 01/2023
2	Hepatic Encephalopathy 08/2023 - 01/2023
2	Metabolic Syndrome (Dysmetabolic Syndrome X) 01/2023 - 01/2020
2	Dyslipidemias (Dyslipidemia) 12/2022 - 10/2021
2	Hyperlipidemias (Hyperlipidemia) 09/2022 - 06/2015
2	Hepatitis 08/2022 - 01/2017
2	Dysbiosis 01/2022 - 10/2020
2	Fatigue 07/2021 - 02/2020
2	Portal Hypertension 01/2021 - 01/2020
2	Cholestasis 02/2020 - 01/2018
2	Cholangiocarcinoma 01/2018 - 01/2017
1	Flushing 02/2024
1	Diarrhea 01/2024

Drug/Important Bio-Agent (IBA)

17	Biomarkers (Surrogate Marker)IBA 12/2023 - 09/2012
9	Triglycerides (Triacylglycerol)IBA 12/2022 - 06/2015
8	Bile Acids and Salts (Bile Acids)IBA 01/2023 - 12/2018
8	Alanine Transaminase (SGPT)IBA 08/2022 - 11/2013
7	LipidsIBA 01/2023 - 01/2021
6	Proteins (Proteins, Gene)FDA Link 11/2023 - 04/2012
6	S-Adenosylmethionine (Ademetionine)IBA 02/2023 - 10/2008
6	Aspartate Aminotransferases (Aspartate Transaminase)IBA 04/2022 - 11/2013
5	cilofexorIBA 01/2023 - 01/2020
5	Transaminases (Aminotransferases)IBA 01/2023 - 09/2016
5	nasIBA 10/2022 - 01/2019
5	firsocostatIBA 01/2022 - 11/2018
5	Antiviral Agents (Antivirals)IBA 11/2018 - 01/2012
5	Ribavirin (Virazole)FDA LinkGeneric 10/2014 - 09/2010
5	InterferonsIBA 10/2014 - 10/2011
4	Protons (Proton)IBA 01/2023 - 11/2018
4	EnzymesIBA 01/2023 - 06/2015
4	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 03/2018
3	obeticholic acidIBA 01/2023 - 01/2018
3	semaglutideIBA 01/2023 - 01/2022
3	belapectinIBA 01/2023 - 01/2020
3	omega-Chloroacetophenone (Mace)IBA 01/2023 - 11/2022
3	Fatty Acids (Saturated Fatty Acids)IBA 01/2022 - 06/2019
3	Insulin (Novolin)FDA Link 01/2022 - 01/2018
2	Peroxisome Proliferator-Activated Receptors (PPAR)IBA 03/2024 - 10/2021
2	Thyroid Hormone Receptors (Thyroid Hormone Receptor)IBA 03/2024 - 01/2024
2	resmetiromIBA 01/2024 - 01/2024
2	ProteomeIBA 02/2023 - 11/2017
2	gamma-Glutamyltransferase (gamma-Glutamyl Transpeptidase)IBA 01/2023 - 01/2020
2	Hypoglycemic Agents (Hypoglycemics)IBA 01/2023 - 01/2022
2	AdiponectinIBA 01/2023 - 10/2021
2	CytokinesIBA 01/2023 - 01/2018
2	Indicators and Reagents (Reagents)IBA 01/2023 - 03/2017
2	RNA (Ribonucleic Acid)IBA 05/2022 - 11/2013
2	SodiumIBA 01/2022 - 03/2017
2	Vitamin E FDA LinkGeneric 01/2022 - 01/2022
2	Hemoglobins (Hemoglobin)IBA 01/2022 - 01/2007
2	Fibric Acids (Fibrates)IBA 01/2022 - 02/2020
2	LipopolysaccharidesIBA 01/2022 - 10/2020
2	Methionine (L-Methionine)FDA Link 01/2022 - 11/2017
2	Pioglitazone (Actos)FDA Link 01/2022 - 01/2022
2	alpha-Fetoproteins (alpha-Fetoprotein)IBA 09/2021 - 01/2020
2	selonsertibIBA 07/2021 - 01/2021
2	Drug CombinationsIBA 07/2021 - 01/2021
2	Galectin 3 (LGALS3)IBA 04/2021 - 01/2020
2	Estrogens (Estrogen)FDA Link 01/2021 - 01/2021
2	DefensinsIBA 10/2020 - 01/2020
2	Vitamin D FDA LinkGeneric 10/2020 - 01/2020
2	Coffee FDA Link 05/2020 - 01/2017
2	InterleukinsIBA 11/2013 - 04/2012
1	Glucagon-Like Peptides (Enteroglucagon)IBA 03/2024
1	Thyroid Hormone Receptors beta (TR beta)IBA 01/2024

Therapy/Procedure

30	Therapeutics 02/2024 - 10/2010
22	Liver Transplantation 03/2024 - 07/2015
5	Drug Therapy (Chemotherapy) 01/2023 - 01/2019
4	Bariatric Surgery 10/2023 - 09/2017
2	Immunotherapy 12/2023 - 11/2023
2	Transplantation 11/2023 - 07/2020